DIP2B — Disco interacting protein 2 homolog B
DIP2B belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DIP2B's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Endothelial Lipid Signaling migration & adhesion | A2M, ADGRG1, ARHGEF15, CNOT6L, CYYR1, HIP1R, PCDH1, PITPNC1 +3 more | View in SCUBA |
| Macrophages | Rho GTPase Signaling Cytoskeletal | ABHD18, AFF1, ARHGEF7, DNAAF9, DOCK11, EVI5, GNAQ, IL1RAP +24 more | View in SCUBA |
| Neutrophils | Endosomal Vesicle Trafficking Vesicular traficking | ELF2, JAK1, NRDC, OSBPL8, PCNX1, PICALM, SLC12A6, TBXAS1 +3 more |
About the gene
| Synonyms | FLJ34278, KIAA1463 |
|---|---|
| Chromosome | 12: 50504985-50748657 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Human disease related genes, Predicted intracellular proteins |
| Biological process | Neurogenesis |
Function
Negatively regulates axonal outgrowth and is essential for normal synaptic transmission. Not required for regulation of axon polarity. Promotes acetylation of alpha-tubulin
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.