AFF1 — ALF transcription elongation factor 1
AFF1 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
AFF1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Spliceosome Regulation RNA processing & translation | ATOSA, CEP95, CSNK1A1, FAM13B, KANSL3, KIF5B, MYSM1, PNN +15 more | |
| Hematopoietic progenitor cells | HOX HSC Program Stemness | ADGRE2, ARHGAP25, HOXA3, HOXA6, HOXA9, JAML, LPIN1, MOB1B +3 more | |
| Macrophages | Rho GTPase Signaling Cytoskeletal | ABHD18, ARHGEF7, DIP2B, DNAAF9, DOCK11, EVI5, GNAQ, IL1RAP +24 more | View in SCUBA |
| Mucosal-associated invariant T cell | TGF-β Immune Regulation Immune regulation | ADAM12, AKAP9, FNBP4, IKZF3, INPP4A, MAN1A1, NSD3, PCNX1 +8 more |
About the gene
| Synonyms | AF-4, AF4, FEL, MLLT2, PBM1 |
|---|---|
| Chromosome | 4: 86935002-87141039 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins |
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.