EAPP — E2F associated phosphoprotein
EAPP belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
EAPP's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Cell cycle regulators DNA/chromatin regulation | CCDC28A, CCNDBP1, CFAP20, IFNAR2, LAPTM4A, RBBP4, SH3GLB1 | View in SCUBA |
| Gamma-delta T cells | Chromatin-Splicing Regulation DNA/chromatin regulation | ANKRD11, BOD1L1, CAMLG, CEBPB, FMR1, KMT2B, MED10, MFSD14A +13 more |
About the gene
| Synonyms | BM036, C14orf11, FLJ20578 |
|---|---|
| Chromosome | 14: 34515938-34539704 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
Function
May play an important role in the fine-tuning of both major E2F1 activities, the regulation of the cell-cycle and the induction of apoptosis. Promotes S-phase entry, and inhibits p14(ARP) expression
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.