CDIPT — CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CDIPT belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CDIPT's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Innate lymphoid cells | ILC1 Lymphocyte Signaling Immune regulation | CNPY3, DBNL, ENG, IL16, LIMD2, LSM2, MAPKAPK3, PHYKPL +11 more | View in SCUBA |
About the gene
| Synonyms | PIS, PIS1 |
|---|---|
| Chromosome | 16: 29858357-29863414 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted membrane proteins |
| Molecular function | Transferase |
| Biological process | Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism |
Function
Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.