ENDOD1 — Endonuclease domain containing 1
ENDOD1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ENDOD1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Lymphatic endothelial | Endothelial Identity endothelial development | CHST12, EPHB4, F2R, F8, GALNT1, KDR, NR2F2, PECAM1 +4 more | View in SCUBA |
About the gene
| Synonyms | KIAA0830 |
|---|---|
| Chromosome | 11: 95089846-95132645 |
| Predicted location | Membrane, Secreted |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted membrane proteins, Predicted secreted proteins |
| Molecular function | Endonuclease, Hydrolase, Nuclease |
| Biological process | Immunity, Innate immunity |
Function
May act as a DNase and a RNase. Plays a role in the modulation of innate immune signaling through the cGAS-STING pathway by interacting with RNF26
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.