ADD1 — Adducin 1
ADD1 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ADD1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Cytoskeletal Scaffolding Cytoskeletal | AGPAT1, ANO6, ARL6IP5, CDC42BPA, CHURC1, DOCK1, ERC1, MAP4 +6 more | View in SCUBA |
| Gamma-delta T cells | Vesicular Trafficking Housekeeping | ANAPC5, COPG1, EFCAB14, EXOC7, GANAB, MAN2B2, MCM3AP, MED1 +10 more | |
| Macrophages | ER-Golgi Trafficking Vesicular traficking | AFTPH, AZIN1, COPA, DYNC1H1, HNRNPC, JOSD1, LCP2, LRRFIP1 +23 more | View in SCUBA |
| Mucosal-associated invariant T cell | Chromatin Epigenetic Regulation DNA/chromatin regulation | ANKRD36, ANKRD36C, CHIC2, ERICH1, ESYT2, KAT6B, MDM4, PACS1 +7 more |
About the gene
| Chromosome | 4: 2843844-2930076 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
| Molecular function | Actin-binding, Calmodulin-binding |
Function
Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.