GCNT3 — Glucosaminyl (N-acetyl) transferase 3, mucin type
GCNT3 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GCNT3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Colonocyte terminal differentiation Epithelial development | CCDC186, CEACAM1, CMPK1, FHL2, HKDC1, IFNGR1, LRRFIP1, PTP4A1 +2 more | View in SCUBA |
About the gene
| Synonyms | C2/4GnT, C2GnT-M, C2GnT2 |
|---|---|
| Chromosome | 15: 59594875-59640239 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins |
| Molecular function | Glycosyltransferase, Transferase |
Function
Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Also has I- branching enzyme activity by converting linear into branched poly-N- acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.