IL21R — Interleukin 21 receptor
IL21R belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
IL21R's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | TNF activation survival Immune regulation | BCL2L1, CD82, CFLAR, CMSS1, EPOP, KCNN4, KDM2B, LTA +12 more | View in SCUBA |
| Gamma-delta T cells | NF-κB Activation Inflammation | DUSP5, GADD45A, HERPUD1, KDM6B, MAFF, NAMPT, NFKB1, NFKB2 +13 more | |
| Mucosal-associated invariant T cell | T cell Quiescence T cell maturation | AGO2, AUTS2, BCL6, BRD1, CSNK1D, DHCR7, FOXO1, GABPB1 +13 more |
About the gene
| Synonyms | CD360 |
|---|---|
| Chromosome | 16: 27402174-27452042 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins |
| Molecular function | Receptor |
Function
This is a receptor for interleukin-21
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.