JAG2 — Jagged canonical Notch ligand 2
JAG2 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
JAG2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | EC Inflammatory Activation Inflammation | ARHGAP4, ARHGEF2, ARL15, ATP13A3, CAPZA2, CD58, GFOD1, GJA4 +12 more | View in SCUBA |
| Pericytes | Notch Vascular Development Developmental | ADAM15, ECSCR, HYAL2, ICAM2, KCNN3, LYL1, MANSC1, NUDT14 +2 more | View in SCUBA |
About the gene
| Chromosome | 14: 105140982-105168824 |
|---|---|
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted membrane proteins |
| Molecular function | Developmental protein |
| Biological process | Notch signaling pathway |
Function
Putative Notch ligand involved in the mediation of Notch signaling. Involved in limb development (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.