LAMC2 — Laminin subunit gamma 2
LAMC2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
LAMC2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Goblet cells | Basement Membrane Remodeling migration & adhesion | AHNAK, CD55, CYP3A5, F3, GPRC5A, LAMA3, LAMB3, LIPH +7 more | View in SCUBA |
About the gene
| Synonyms | BM600-100kDa, EBR2, EBR2A, kalinin-105kDa, LAMB2T, LAMNB2, nicein-100kDa |
|---|---|
| Chromosome | 1: 183186238-183245127 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins |
| Molecular function | Heparin-binding |
| Biological process | Cell adhesion |
Function
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Ladsin exerts cell-scattering activity toward a wide variety of cells, including epithelial, endothelial, and fibroblastic cells
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.