LAMB3 — Laminin subunit beta 3
LAMB3 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
LAMB3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | JUN stress response Stress | FOXO3, H1-2, H2AC6, JUN, LAMA3, PTPRB, ZNF292 | View in SCUBA |
| Goblet cells | Basement Membrane Remodeling migration & adhesion | AHNAK, CD55, CYP3A5, F3, GPRC5A, LAMA3, LAMC2, LIPH +7 more | View in SCUBA |
| Monocytes | TNF-driven Activation Inflammatory | ATP13A3, CD44, DCUN1D3, DSE, GK, IVNS1ABP, LITAF, POMP +3 more | View in SCUBA |
| Pericytes | Basement Membrane Remodeling ECM remodeling | ADA, C4orf48, CYBA, DKK3, EFEMP2, G0S2, ISG20, RCN3 +2 more | View in SCUBA |
About the gene
| Synonyms | BM600-125kDa, kalinin-140kDa, LAMNB1, nicein-125kDa |
|---|---|
| Chromosome | 1: 209614870-209652425 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins |
| Biological process | Cell adhesion |
Function
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.