SCUBA

FNDC3B — Fibronectin type III domain containing 3B

FNDC3B belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

FNDC3B's module in each cell type

Cell typeModuleShares the module with
CD4⁺ T cellsImmune Regulation
Immune regulation
ADAT2, AFTPH, C2CD4B, CDKL2, CPEB4, DDHD1, FAM53B, FAS +10 moreView in SCUBA
EndothelialInflammatory EC Activation
Inflammation
FJX1, GPR4, HK1, ITGA5, MAP1S, MCAM, MSN, P2RY6 +3 moreView in SCUBA
EnterocytesBasal adhesion remodeling
Migration & adhesion
EPB41L2, ETS2, HERC4, ITGA6, NT5C2, SESTD1, SGMS1, SH3RF1 +2 moreView in SCUBA
FibroblastsBasement Membrane ECM
ECM production
BSG, COL6A1, COL6A2, COMT, ECE1, ECM1, LAMB1, LAMC1 +2 moreView in SCUBA
Gamma-delta T cellsLysosomal Biogenesis
Protein processing & ER
ABI3, APLP2, ATP10A, B3GALT4, BAX, CD63, CTNNA1, DOCK5 +14 more
Lymphatic endothelialMAPK-ERK Signaling
migration & adhesion
ARIH1, BRAF, CPNE8, DENND4A, ELF2, FBXO11, GRB10, NT5C2 +6 moreView in SCUBA
MacrophagesHypoxia-driven Activation
Inflammatory
ACVR1B, ADAM10, ADAM9, ALCAM, ANO6, B3GNT2, BTG1, C5AR1 +33 moreView in SCUBA
PericytesInflammatory ECM Remodeling
ECM remodeling
CASP4, CHSY1, GMFG, ITPRIPL2, LAMB1, MARCKSL1, NECTIN2, OLFML2A +5 moreView in SCUBA

About the gene

SynonymsDKFZp762K137, FAD104, FLJ23399, PRO4979, YVTM2421
Chromosome3: 172039578-172401669
Predicted locationIntracellular, Membrane
Essential geneNo
Protein classPredicted intracellular proteins, Predicted membrane proteins

Function

May be a positive regulator of adipogenesis

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.