SCUBA

LAMC3 — Laminin subunit gamma 3

LAMC3 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

LAMC3's module in each cell type

Cell typeModuleShares the module with
FibroblastsLamina Propria ECM
ECM production
ADAMTS7, ADGRL4, ANGPTL6, BMP2, CBLN2, CYTL1, DHRS7C, FAM135B +14 moreView in SCUBA
PericytesFibrotic ECM Remodeling
ECM remodeling
BGN, CYGB, LGALS3BP, LPL, MMP11, NREP, PCDH18, PLOD2 +2 moreView in SCUBA

About the gene

SynonymsDKFZp434E202
Chromosome9: 131009174-131094473
Predicted locationIntracellular, Secreted
Essential geneNo
Protein classDisease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Biological processCell adhesion

Function

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.