LGALS3BP — Galectin 3 binding protein

LGALS3BP belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

LGALS3BP's module in each cell type

Cell type	Module	Shares the module with
Fibroblasts	Lysosomal Biogenesis Vesicular traficking	APP, ATRAID, CPQ, CST3, GLG1, GRN, HEXA, NDN +5 more	View in SCUBA
Gamma-delta T cells	Naïve T Cell State T cell maturation	ARL14EP, CCR2, CD27, CD28, CD40LG, CD82, CNN2, CPNE2 +19 more
Glial cells	MHC-I Antigen Presentation Inflammation	B2M, BTN3A2, C1R, C1S, CST3, HLA-A, HLA-B, HLA-C +4 more	View in SCUBA
Goblet cells	Mucosal Innate Defense Immune function	BOLA3, CTSS, DMBT1, ENO1, GPI, OLFM4, PIGR, PLA2G2A +4 more	View in SCUBA
Macrophages	Innate Antiviral Sensing Innate immunity	ADA2, ADPRH, ALDH9A1, APOBEC3C, BST2, C2, CAT, CD4 +26 more	View in SCUBA
Monocytes	Immunoproteasome Antigen Processing Innate immunity	APOL1, APOL4, FBXO6, IFI27, IFI35, PSMB8, PSMB9, PSME1 +5 more	View in SCUBA
Pericytes	Fibrotic ECM Remodeling ECM remodeling	BGN, CYGB, LAMC3, LPL, MMP11, NREP, PCDH18, PLOD2 +2 more	View in SCUBA
Smooth muscle cells	Adhesion Activation Migration & adhesion	ANXA2, ATP1B3, CAPNS1, CD44, CYBRD1, FHL2, LAMC1, LGALS3 +3 more	View in SCUBA

About the gene

Synonyms	90K, BTBD17B, CyCAP, gp90, M2BP, MAC-2-BP, TANGO10B
Chromosome	17: 78971238-78979947
Predicted location	Secreted
Essential gene	No
Protein class	Cancer-related genes, Plasma proteins, Predicted secreted proteins
Biological process	Cell adhesion

Function

Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.