MTCL1 — Microtubule crosslinking factor 1
MTCL1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MTCL1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Smooth Muscle Identity Cytoskeletal | ACTG2, ALDH1B1, C3orf70, CNN1, FBXL22, HSD17B6, JPH2, KCNH2 +12 more | View in SCUBA |
About the gene
| Synonyms | CCDC165, KIAA0802, SOGA2 |
|---|---|
| Chromosome | 18: 8705556-8832778 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
| Biological process | Cell cycle, Cell division, Mitosis |
Function
Microtubule-associated factor involved in the late phase of epithelial polarization and microtubule dynamics regulation. Plays a role in the development and maintenance of non-centrosomal microtubule bundles at the lateral membrane in polarized epithelial cells. Required for faithful chromosome segregation during mitosis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.