SCUBA

PGGHG — Protein-glucosylgalactosylhydroxylysine glucosidase

PGGHG belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

PGGHG's module in each cell type

Cell typeModuleShares the module with
CD4⁺ T cellsTranscriptional regulation
DNA/chromatin regulation
CCNH, CWC25, DYNLL2, EIF2A, GOLGB1, IVNS1ABP, JMJD1C, KRR1 +8 moreView in SCUBA
Gamma-delta T cellsEOMES Effector Program
T cell maturation
AGK, ANKZF1, ATG16L2, C6orf120, CARD8, CBX1, CDK5RAP3, CENPT +25 more
Innate lymphoid cellsNK Cytokine Signaling
Immune regulation
BORCS7, C6orf62, DDX18, IER3, LMO4, MAT2A, NSUN6, PLCG2 +3 moreView in SCUBA
Smooth muscle cellsHOX Positional Identity
Development
AC027644.3, AC092164.1, AL139246.5, FAM122A, FAM241A, GRAMD2B, HOXB-AS1, HOXB-AS3 +10 moreView in SCUBA

About the gene

SynonymsATHL1, FLJ22635
Chromosome11: 289126-296107
Predicted locationIntracellular
Essential geneNo
Protein classEnzymes, Metabolic proteins, Predicted intracellular proteins
Molecular functionGlycosidase, Hydrolase

Function

Catalyzes the hydrolysis of glucose from the disaccharide unit linked to hydroxylysine residues of collagen and collagen-like proteins

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.