S100P — S100 calcium binding protein P
S100P belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
S100P's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Goblet cells | S100 Calcium Signaling Stress | CIB1, CLDN7, CLTB, GUK1, MYL12B, MYL6, RHOC, S100A11 +4 more | View in SCUBA |
| Monocytes | Monocyte Innate Surveillance Innate immunity | CDKN2D, FCN1, ICAM3, MMP25, PADI2, RPH3A, TESC, TUBA4A | View in SCUBA |
| Neutrophils | Actin Cytoskeleton Dynamics Cytoskeletal | ACTB, ACTG1, ARPC5, CFL1, CORO1A, ITGB2, MYL6, PFN1 +6 more |
About the gene
| Chromosome | 4: 6693878-6697170 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
Function
May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.