SCUBA

S100A11 — S100 calcium binding protein A11

S100A11 belongs to a gene co-expression module in 14 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

S100A11's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsCytoskeleton/motility
migration & adhesion
ANXA2, ANXA4, BHLHE41, C4orf48, CAPG, CAPN2, CIB1, ISCU +11 moreView in SCUBA
CD4⁺ T cellsCytotoxic effector
Cytotoxicity
ADAM23, CTSW, EMP3, FKBP2, IFITM2, IGFBP3, KLRG1, LYAR +11 moreView in SCUBA
EndothelialOxidative Stress Response
Stress
AHR, CD151, CD59, CTTNBP2NL, DSTN, FLOT2, GNB4, GNG5 +11 moreView in SCUBA
FibroblastsRho GTPase Cytoskeletal
Cytoskeletal
APRT, CLIC1, CYBA, HSBP1, LY6E, RAB34, RHOA, RHOC +2 moreView in SCUBA
Gamma-delta T cellsT Cell Survival
T cell maturation
CASP1, CCDC107, CTU1, GEMIN7, GIMAP1, GIMAP2, GIMAP4, GIMAP5 +13 more
Glial cellsProteasomal Proteostasis
Protein processing & ER
CD63, CLIC1, COX7A2, ELOB, MYL12B, PDIA6, PSMA7, PSMB1 +3 moreView in SCUBA
Goblet cellsS100 Calcium Signaling
Stress
CIB1, CLDN7, CLTB, GUK1, MYL12B, MYL6, RHOC, S100A13 +4 moreView in SCUBA
Innate lymphoid cellsAntigen Processing MHC-I
Immune regulation
CMTM6, GUK1, IL2RB, IL4R, MYL12A, PAXX, PSMA5, PSMB8 +8 moreView in SCUBA
Lymphatic endothelialOxidative Stress Response
Stress
ANXA5, ATP6V0B, CCT3, CD59, DRAP1, EIF5A, GPX4, NUPR1 +3 moreView in SCUBA
MacrophagesGlycolytic Redox Metabolism
Lipid metabolism
AGPAT2, ANXA5, ATP6V1F, BCKDK, BRI3, C1orf122, CLIC1, ELOC +18 moreView in SCUBA
Mucosal-associated invariant T cellER & Mitochondrial Assembly
Protein processing & ER
ANAPC11, ARRDC1, ATP5MC1, COA3, CSTB, DECR1, GSTK1, HINT2 +9 more
Natural Killer cellsActin Cytoskeleton Remodeling
Cytoskeleton & motility
ABRACL, ARPC3, ARPC5, ATP5F1D, DRAP1, MYL12B, MYL6, PRDX2 +2 moreView in SCUBA
NeutrophilsMyeloid Identity
Housekeeping
ANP32A, CKLF, CMTM2, HLA-C, HLA-E, IFITM2, ITM2B, LST1 +3 more
Smooth muscle cellsNon-muscle Actomyosin
Cytoskeletal
C1R, CAST, CD63, CLIC1, DYNLL1, FILIP1L, LDHA, LIMS1 +4 moreView in SCUBA

About the gene

SynonymsS100C
Chromosome1: 152032506-152047907
Predicted locationIntracellular
Essential geneNo
Protein classPlasma proteins, Predicted intracellular proteins

Function

Facilitates the differentiation and the cornification of keratinocytes

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.