CLDN7 — Claudin 7
CLDN7 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CLDN7's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Actin cytoskeleton Cytoskeletal | ACTB, ACTG1, CAST, CDC42EP5, JPT1, MYL12B, PIGR, TMEM54 | View in SCUBA |
| Goblet cells | S100 Calcium Signaling Stress | CIB1, CLTB, GUK1, MYL12B, MYL6, RHOC, S100A11, S100A13 +4 more | View in SCUBA |
| Macrophages | Lysosomal Hydrolase Program Lysosomal & pahgocytosis | AMDHD2, ARL6IP5, ARPIN, ARSA, CD81, CLEC2B, COMT, CTSS +35 more | View in SCUBA |
About the gene
| Synonyms | CEPTRL2, CPETRL2, Hs.84359 |
|---|---|
| Chromosome | 17: 7259903-7263983 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
Function
Plays a major role in tight junction-specific obliteration of the intercellular space
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.