CLTB — Clathrin light chain B
CLTB belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CLTB's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Mitochondrial OxPhos Mitochondrial & OxPhos | AP2M1, ATP5MF, ATP6V0B, AURKAIP1, BSG, CALM3, CSNK2B, ERH +19 more | View in SCUBA |
| Endothelial | Mitochondrial OxPhos Mitochondrial & OxPhos | ARPC3, COX6A1, COX7A2, COX7B, DAD1, ELOB, MYL12B, NDUFA11 +9 more | View in SCUBA |
| Goblet cells | S100 Calcium Signaling Stress | CIB1, CLDN7, GUK1, MYL12B, MYL6, RHOC, S100A11, S100A13 +4 more | View in SCUBA |
| Innate lymphoid cells | DNA Damage Response Stress | ANP32E, CCT6A, FGFR1OP2, GNL3, HNRNPF, JPT1, MRPS6, PDCD10 +7 more | View in SCUBA |
| Macrophages | Mitochondrial OXPHOS Mitochondrial & OxPhos | APRT, ARPC3, ATP5F1E, ATP5MF, ATP5MG, BLOC1S1, BTF3, COX4I1 +28 more | View in SCUBA |
| Smooth muscle cells | OXPHOS Complex I Mitochondrial & OxPhos | COPS6, ETFB, IAH1, MRPS21, NDUFA2, NDUFB10, NDUFC2, OAT +3 more | View in SCUBA |
About the gene
| Synonyms | Lcb |
|---|---|
| Chromosome | 5: 176392501-176416539 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins, Transporters |
Function
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.