SLC35D2 — Solute carrier family 35 member D2
SLC35D2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SLC35D2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | B-cell antigen presentation B cell maturation | APBB1IP, BMP2K, BTN2A2, CIITA, CYTH4, EVL, HHEX, MS4A1 +6 more | View in SCUBA |
About the gene
| Synonyms | SQV7L, UGTrel8 |
|---|---|
| Chromosome | 9: 96313444-96383711 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Metabolic proteins, Predicted membrane proteins, Transporters |
| Biological process | Antiport, Sugar transport, Transport |
Function
Nucleotide sugar antiporter transporting UDP-N- acetylglucosamine (UDP-GlcNAc) and UDP-glucose (UDP-Glc) from the cytosol into the lumen of the Golgi in exchange of UMP. By supplying UDP-N-acetylglucosamine, a donor substrate to heparan sulfate synthases, probably takes part in the synthesis of these glycoconjugates.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.