APBB1IP — Amyloid beta precursor protein binding family B member 1 interacting protein

APBB1IP belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

APBB1IP's module in each cell type

Cell type	Module	Shares the module with
CD19⁺ B cells	B-cell antigen presentation B cell maturation	BMP2K, BTN2A2, CIITA, CYTH4, EVL, HHEX, MS4A1, SLC35D2 +6 more	View in SCUBA
CD4⁺ T cells	Effector Immune Activation Immune regulation	ABI3, ASB2, BUB3, CALCOCO2, CASP4, COMMD7, CTSD, CXCR6 +7 more	View in SCUBA
Fibroblasts	Subepithelial Fibroblast Identity Developmental	ANGPTL1, ARHGAP15, CNTN1, CP, ECM2, EFEMP1, FAM107A, FGF13 +12 more	View in SCUBA
Gamma-delta T cells	Actin-based Motility Cytoskeletal	CD58, COMMD7, CORO1B, CTSD, EVL, FDFT1, HMOX2, OSTF1 +13 more
Innate lymphoid cells	Actin Cytoskeleton Dynamics Cytoskeleton & motility	ACTN4, ALDH9A1, ARHGAP10, CDC37, CXXC5, FAM136A, FERMT3, FIP1L1 +26 more	View in SCUBA
Mucosal-associated invariant T cell	Chromatin Epigenetic Regulation DNA/chromatin regulation	ACAP2, ARHGAP25, ATM, CD247, CHD9, CLCN3, DDX17, FLI1 +14 more
Natural Killer cells	Resident NK cells Gut residency	ANXA11, CD151, CXXC5, HMOX2, LSP1, MPG, PPDPF, SH3BP1 +4 more	View in SCUBA
Neutrophils	Stress Kinase Signaling Stress	ANKRD44, HIPK3, IGF1R, MAP3K5, MEF2A, NEK7, PARP8, RAP1GAP2 +2 more

About the gene

Synonyms	INAG1, RIAM
Chromosome	10: 26438341-26567803
Predicted location	Intracellular
Essential gene	No
Protein class	Predicted intracellular proteins

Function

Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.