SSC5D — Scavenger receptor cysteine rich family member with 5 domains
SSC5D belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SSC5D's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Elastin-Fibronectin ECM ECM production | ABI3BP, DDAH2, ELN, FN1, LRIG3, S100A4, SERPINE2, SOD3 | View in SCUBA |
| Smooth muscle cells | Neural Adhesion Program Development | CHL1, CNTN4, DSEL, EMID1, F3, IGFBP3, MATN2, STMN2 +1 more | View in SCUBA |
About the gene
| Synonyms | FLJ35258, S5D-SRCRB |
|---|---|
| Chromosome | 19: 55488404-55519099 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted secreted proteins |
| Molecular function | Developmental protein, Receptor |
| Biological process | Immunity, Innate immunity |
Function
Binds to extracellular matrix proteins. Binds to pathogen- associated molecular patterns (PAMPs) present on the cell walls of Gram-positive and Gram-negative bacteria and fungi, behaving as a pattern recognition receptor (PRR). Induces bacterial and fungal aggregation and subsequent inhibition of PAMP-induced cytokine release. Does not possess intrinsic bactericidal activity. May play a role in the innate defense and homeostasis of certain epithelial surfaces (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.