SOD3 — Superoxide dismutase 3
SOD3 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SOD3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Elastin-Fibronectin ECM ECM production | ABI3BP, DDAH2, ELN, FN1, LRIG3, S100A4, SERPINE2, SSC5D | View in SCUBA |
| Glial cells | Enteric Glial Homeostasis Housekeeping | APOE, BCHE, CCND3, COL12A1, ENTPD2, FXYD6, NPDC1, PAQR6 +5 more | View in SCUBA |
| Goblet cells | Secreted Antimicrobials Immune function | FAM3D, IFI6, IGFBP2, KLK11, KLK12, NBL1, NOXO1, PCSK1 +6 more | View in SCUBA |
| Pericytes | Pericyte Vascular Tone Developmental | ADAP2, CHCHD10, CSPG4, FOXS1, LINGO1, MCAM, MFGE8, PGF +3 more | View in SCUBA |
| Smooth muscle cells | Contractile SMC Identity Contractility | C11orf96, CPE, FHL5, MAP7D3, NFIB, PTGIR, SLC7A2, SORBS3 | View in SCUBA |
About the gene
| Synonyms | EC-SOD |
|---|---|
| Chromosome | 4: 24789912-24800842 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins |
| Molecular function | Antioxidant, Heparin-binding, Oxidoreductase |
Function
Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.