TBCC — Tubulin folding cofactor C
TBCC belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TBCC's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | TCR signaling TCR/AP1/NFKb pathway | AP3M2, ATP1B3, CREM, CRYBG1, DCTN6, EZR, FAM177A1, FTH1 +19 more | View in SCUBA |
| Gamma-delta T cells | AP-1 Immediate Early Response Stress | BRD2, CITED2, CSKMT, EGR1, EIF4A2, FRAT1, FRAT2, GADD45B +25 more | |
| Mucosal-associated invariant T cell | Mitochondrial Quality Control Mitochondrial & OxPhos | COQ7, EPS8, LETM2, PATL2, SDR42E2, YME1L1, ZBTB10 |
About the gene
| Synonyms | CFC |
|---|---|
| Chromosome | 6: 42744498-42746103 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Chaperone |
Function
Tubulin-folding protein; involved in the final step of the tubulin folding pathway
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.