TMEM132A — Transmembrane protein 132A
TMEM132A belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TMEM132A's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Inflammatory ECM Remodeling ECM remodeling | ABRACL, ADAMTS2, CD82, CHI3L1, COTL1, GGCT, LXN, MT2A +5 more | View in SCUBA |
| Goblet cells | Progenitor Identity Program Epithelial development | APEX1, FAM89B, MAP4K4, MEX3A, NOTCH1, NREP, RNF186, SOX4 +3 more | View in SCUBA |
About the gene
| Synonyms | FLJ20539, GBP, HSPA5BP1 |
|---|---|
| Chromosome | 11: 60924460-60937159 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins, Transporters |
Function
May play a role in embryonic and postnatal development of the brain. Increased resistance to cell death induced by serum starvation in cultured cells. Regulates cAMP-induced GFAP gene expression via STAT3 phosphorylation (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.