TP53I3 — Tumor protein p53 inducible protein 3
TP53I3 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TP53I3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | p53 Stress Response Stress | BACE2, COPS9, NT5C, OST4, PDLIM1, PGLS, POLR2L, RFXANK +1 more | View in SCUBA |
About the gene
| Synonyms | PIG3 |
|---|---|
| Chromosome | 2: 24077433-24085861 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Predicted intracellular proteins |
| Molecular function | Oxidoreductase |
Function
Catalyzes the NADPH-dependent reduction of quinones. Exhibits a low enzymatic activity with beta- naphthoquinones, with a strong preference for the ortho-quinone isomer (1,2-beta-naphthoquinone) over the para isomer (1,4-beta- naphthoquinone). Also displays a low reductase activity for non-quinone compounds such as diamine and 2,6-dichloroindophenol (in vitro). Involved in the generation of reactive oxygen species (ROS)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.