PGLS — 6-phosphogluconolactonase
PGLS belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PGLS's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Leukocyte adhesion signaling migration & adhesion | ARHGDIB, BIN1, CD37, DGKA, DGKZ, EIF3F, EIF3L, EIF4B +22 more | View in SCUBA |
| Endothelial | p53 Stress Response Stress | BACE2, COPS9, NT5C, OST4, PDLIM1, POLR2L, RFXANK, SEM1 +1 more | View in SCUBA |
| Gamma-delta T cells | Complex I Assembly Mitochondrial & OxPhos | AKR7A2, AP2S1, BLOC1S1, DCTN2, HSD17B10, LAMTOR2, MGMT, MRPL34 +13 more | |
| Innate lymphoid cells | ILC-1 identity Differentiation | ABRACL, BLOC1S1, C19orf53, CD52, DAD1, FUCA2, GMFG, HMGN3 +20 more | View in SCUBA |
| Macrophages | Mitochondrial OXPHOS Mitochondrial & OxPhos | ATP5IF1, ATP5MC2, ECH1, FAM89B, GMFG, GSTP1, HIGD2A, LAMTOR4 +9 more | View in SCUBA |
| Mucosal-associated invariant T cell | Oxidative Stress Response Stress | CDC42EP3, CTU1, EXOSC5, GLRX, GNPDA1, HTATIP2, KRCC1, MLX +11 more |
About the gene
| Synonyms | 6PGL |
|---|---|
| Chromosome | 19: 17511636-17521288 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Hydrolase |
Function
Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.