VAT1 — Vesicle amine transport 1
VAT1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
VAT1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | ER-Lysosome Trafficking Vesicular traficking | BPNT2, CALU, CLPTM1L, CTSB, DHRS7, EMC10, GBA1, GNS +21 more | View in SCUBA |
| Pericytes | YAP/TAZ Mechanosensing Developmental | CARHSP1, COL15A1, ENG, MLEC, NOL4L, TMEM204, TRIOBP, WWTR1 +1 more | View in SCUBA |
About the gene
| Synonyms | FLJ20230, VATI |
|---|---|
| Chromosome | 17: 43014607-43025123 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
| Molecular function | Oxidoreductase |
Function
Possesses ATPase activity (By similarity). Plays a part in calcium-regulated keratinocyte activation in epidermal repair mechanisms. Has no effect on cell proliferation. Negatively regulates mitochondrial fusion in cooperation with mitofusin proteins (MFN1-2).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.