VMA21 — Vacuolar ATPase assembly factor VMA21
VMA21 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
VMA21's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Respiratory chain assembly Mitochondrial & OxPhos | COA4, COA6, CYC1, EBNA1BP2, ERCC1, POLR2E, PRELID3B, PSMD3 | View in SCUBA |
| Endothelial | DNA Damage Repair DNA/chromatin regulation | APPL1, GPAA1, HMGB1, HNRNPM, HNRNPR, NAP1L4, NCL, PRDX3 +7 more | View in SCUBA |
| Macrophages | Glycolytic Metabolism Housekeeping | ARL1, ARPC5, ATP5PB, ATRAID, C4orf3, CALM1, CAPZA2, CHMP5 +30 more | View in SCUBA |
About the gene
| Synonyms | MEAX, XMEA |
|---|---|
| Chromosome | X: 151396515-151409364 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted membrane proteins |
Function
Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.