SCUBA

HNRNPR — Heterogeneous nuclear ribonucleoprotein R

HNRNPR belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

HNRNPR's module in each cell type

Cell typeModuleShares the module with
CD4⁺ T cellsOxPhos & redox
Mitochondrial & OxPhos
ATOX1, CHCHD2, KIF5B, MRPS21, NDUFAB1, NDUFB1, NDUFB2, POMP +5 moreView in SCUBA
CD8⁺ T cellsNuclear RNA Splicing
RNA processing & translation
CBX3, DNAJC8, HNRNPA3, HNRNPD, MAZ, PGP, PPIG, PSMD1 +5 moreView in SCUBA
EndothelialDNA Damage Repair
DNA/chromatin regulation
APPL1, GPAA1, HMGB1, HNRNPM, NAP1L4, NCL, PRDX3, PRKDC +7 moreView in SCUBA
Gamma-delta T cellsmRNA Splicing
RNA processing & translation
ARHGDIA, DDX27, DDX59, EIF2AK1, EWSR1, FBXL5, GNL1, GTF2F1 +14 more
Goblet cellshnRNP RNA Processing
RNA processing & translation
CCT2, HNRNPAB, HNRNPD, ILF3, IMPA2, SERBP1, SET, TAF15View in SCUBA
Hematopoietic progenitor cellsDNA Damage Repair
Housekeeping
GSPT1, LARS1, MSH6, NCL, PARP1, PRKDC, SUPT16H
Innate lymphoid cellsmTOR Metabolic Stress
Stress
ADPGK, AKR1A1, ATP5IF1, BAX, CPNE1, GLO1, GSTO1, JAGN1 +9 moreView in SCUBA
MacrophagesRNA Processing & Repair
Housekeeping
BRD7, CCDC59, CCT4, CCT6A, CNDP2, EIF3J, EIF5B, EMC4 +31 moreView in SCUBA

About the gene

SynonymshnRNP-R, HNRPR
Chromosome1: 23303771-23344336
Predicted locationIntracellular
Essential geneNo
Protein classPlasma proteins, Predicted intracellular proteins
Molecular functionRibonucleoprotein, RNA-binding
Biological processmRNA processing, mRNA splicing

Function

Component of ribonucleosomes, which are complexes of at least 20 other different heterogeneous nuclear ribonucleoproteins (hnRNP). hnRNP play an important role in processing of precursor mRNA in the nucleus

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.