GPAA1 — Glycosylphosphatidylinositol anchor attachment 1
GPAA1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GPAA1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | DNA Damage Repair DNA/chromatin regulation | APPL1, HMGB1, HNRNPM, HNRNPR, NAP1L4, NCL, PRDX3, PRKDC +7 more | View in SCUBA |
| Gamma-delta T cells | Basal Cell Maintenance Housekeeping | ARHGDIB, CYB561D2, DNAJC8, INO80E, LMF2, MIF4GD, OTUB1, PCYT2 +9 more | |
| Innate lymphoid cells | Ubiquitin Stress Response Stress | AIP, AK2, AP2A1, ARMC10, IAH1, NSFL1C, PHF5A, TRADD +2 more | View in SCUBA |
About the gene
| Synonyms | GAA1, hGAA1 |
|---|---|
| Chromosome | 8: 144082337-144093149 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins |
| Biological process | GPI-anchor biosynthesis |
Function
Component of the glycosylphosphatidylinositol-anchor (GPI- anchor) transamidase (GPI-T) complex that catalyzes the formation of the linkage between a proprotein and a GPI-anchor and participates in GPI anchored protein biosynthesis. Binds GPI-anchor.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.