WBP11 — WW domain binding protein 11
WBP11 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
WBP11's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Pre-mRNA Splicing RNA processing & translation | BCLAF1, CENPC, CLK1, CNOT1, COG3, COPS2, DDX24, DDX3X +11 more | |
| Macrophages | Ubiquitin-ERAD Proteostasis Housekeeping | GSPT1, HSPA9, ITCH, MAPK1IP1L, PANK3, PJA2, SEL1L, TOR1AIP2 +1 more | View in SCUBA |
About the gene
| Synonyms | BUG13, NPWBP, PPP1R165, SIPP1 |
|---|---|
| Chromosome | 12: 14784582-14803486 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins |
| Biological process | mRNA processing, mRNA splicing, rRNA processing |
Function
Activates pre-mRNA splicing. May inhibit PP1 phosphatase activity.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.