ZFYVE16 — Zinc finger FYVE-type containing 16
ZFYVE16 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ZFYVE16's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Oxidative/ER stress Stress | ASAH1, ATP6V0D1, B4GALT1, FAM210A, FOSL2, GEM, GZF1, HIC1 +6 more | View in SCUBA |
| Macrophages | Lipid-Sensing Transcriptional Lipid metabolism | ANKLE2, BAIAP2, C19orf25, C1orf52, COX19, CWC25, DEDD2, DNTTIP2 +29 more | View in SCUBA |
| Monocytes | IRF1 Innate Activation Innate immunity | BAZ1A, CFLAR, FNIP2, IRF1, MARCKS, NABP1, THAP2, TRIM69 | View in SCUBA |
About the gene
| Synonyms | KIAA0305, PPP1R69 |
|---|---|
| Chromosome | 5: 80408013-80483379 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Transporters |
Function
May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.