Ribosomal proteins
Gene co-expression module in CD4⁺ T cells
| Category | Housekeeping |
|---|---|
| Genes | 8 |
| Annotation certainty | 4 of 5 |
| Annotation consistency | 4 of 8 genes have a known function matching the annotation |
Why this annotation
Top hubs are ribosomal protein genes (RPS19, RPLP1, RPLP0) plus TPT1, the highest-expression module (mean 2.1, 61% positive). This is a classic ribosomal/translation housekeeping signature, likely reflecting basal translational machinery. Minimal disease association.
Genes
CD48, ESD, PARP11, RPLP0, RPLP1, RPS19, TPT1, VEGFB
Most correlated modules
- TCR signaling · correlation 0.80
- Resting memory T cell · correlation 0.74
- Cytotoxic effector · correlation 0.69
- T cell quiescence · correlation 0.66
- Cytokine signaling · correlation 0.59
- Naive T cell · correlation 0.59
- Unfolded Protein Response · correlation 0.52
- T cell signaling · correlation 0.51
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.