ESD — Esterase D
ESD belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ESD's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Ribosomal proteins Housekeeping | CD48, PARP11, RPLP0, RPLP1, RPS19, TPT1, VEGFB | View in SCUBA |
| Fibroblasts | Translation Initiation Housekeeping | CCNI, CD99, CNBP, EIF3E, EIF3F, HNRNPA1, ITM2B, LAPTM4A +3 more | View in SCUBA |
| Innate lymphoid cells | Oxidative Phosphorylation Mitochondrial & OxPhos | APEX1, ATP5F1A, CCNC, COA3, DMAC1, HDAC2, HINT2, LAMTOR1 +15 more | View in SCUBA |
| Lymphatic endothelial | Metabolic Housekeeping Housekeeping | CAPNS1, CYB5R3, DMAC1, DUT, EID1, GNAI2, ISCU, OCIAD1 +5 more | View in SCUBA |
| Macrophages | Glycolytic Metabolism Housekeeping | ARL1, ARPC5, ATP5PB, ATRAID, C4orf3, CALM1, CAPZA2, CHMP5 +30 more | View in SCUBA |
About the gene
| Chromosome | 13: 46771256-46797420 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Hydrolase, Serine esterase |
Function
Serine hydrolase involved in the detoxification of formaldehyde
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.