SCUBA

NDUFB8 — NADH:ubiquinone oxidoreductase subunit B8

NDUFB8 belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

NDUFB8's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsOxidative Phosphorylation
Mitochondrial & OxPhos
ANAPC11, AP2S1, ATP5F1A, ATP5F1C, COPE, COX8A, GAPDH, GNG5 +7 moreView in SCUBA
CD4⁺ T cellsOxidative Phosphorylation
Mitochondrial & OxPhos
AP2S1, ATP5F1C, ATP5PF, COPS9, COX6B1, EID1, FAM89B, FDPS +19 moreView in SCUBA
EnterocytesElectron Transport Chain
Mitochondrial & OxPhos
ATP5MG, ATP5MJ, ATP5PD, ATP5PO, COX5B, COX6B1, COX7B, COX7C +6 moreView in SCUBA
Gamma-delta T cellsOxidative Phosphorylation
Mitochondrial & OxPhos
ARPC1B, ARPC4, ATP6V1F, COPE, COX6A1, COX6B1, COX6C, CSNK2B +12 more
Innate lymphoid cellsMitochondrial OxPhos
Mitochondrial & OxPhos
AKR7A2, ANXA6, AP2M1, ARL6IP4, ARPC1B, ATP5MC2, ATP5PB, BSG +21 moreView in SCUBA
Lymphatic endothelialOxidative Phosphorylation
Mitochondrial & OxPhos
ATP5F1C, ATP5IF1, ATP5MC1, ATP5MC3, ATP5MF, ATP5PD, ATP5PF, ATP5PO +5 moreView in SCUBA
MacrophagesMitochondrial OXPHOS
Mitochondrial & OxPhos
APRT, ARPC3, ATP5F1E, ATP5MF, ATP5MG, BLOC1S1, BTF3, CLTB +28 moreView in SCUBA
Smooth muscle cellsUbiquitous Housekeeping Transcripts
Housekeeping
ATP6V1G1, C12orf57, CIRBP, FIS1, GSTP1, ISCU, NUPR1, PEBP1 +3 moreView in SCUBA

About the gene

SynonymsASHI, CI-ASHI
Chromosome10: 100523740-100530000
Predicted locationMembrane
Essential geneNo
Protein classDisease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins
Biological processElectron transport, Respiratory chain, Transport

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.