ABHD17C — Abhydrolase domain containing 17C, depalmitoylase
ABHD17C belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ABHD17C's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Interferon Response Inflammatory | A4GALT, ABCA1, BASP1, CCL7, CLEC2B, IFI16, IFI6, PLSCR1 +5 more | View in SCUBA |
| Monocytes | Secretory Vesicle Trafficking Vesicular traficking | CTNNBL1, DHRS3, FAM20C, HMGA1, NRIP1, PCBP3, SEMA3F, STX1A +1 more | View in SCUBA |
About the gene
| Synonyms | FAM108C1 |
|---|---|
| Chromosome | 15: 80679684-80755621 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Predicted intracellular proteins |
| Molecular function | Hydrolase |
Function
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins. Has depalmitoylating activity towards NRAS and DLG4/PSD95
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.