CAB39 — Calcium binding protein 39
CAB39 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CAB39's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Transcriptional Repressor Complex DNA/chromatin regulation | BAG1, CLEC2B, EBP, FBXO31, GFI1, MAN1A1, MAP2K1, MFSD6 +14 more | |
| Macrophages | Hypoxia-driven Activation Inflammatory | ACVR1B, ADAM10, ADAM9, ALCAM, ANO6, B3GNT2, BTG1, C5AR1 +33 more | View in SCUBA |
| Neutrophils | Signal Attenuation Innate immunity | AGO4, CBL, EXOC6, NPEPPS, PIK3CD, RNF24, SPOPL, ZNF516 |
About the gene
| Synonyms | CGI-66, MO25 |
|---|---|
| Chromosome | 2: 230712842-230821075 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
Function
Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.