FBLN2 — Fibulin 2
FBLN2 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
FBLN2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Inflammatory ECM Remodeling ECM remodeling | ABI3BP, ADRA2C, ANXA3, CGNL1, CLIC3, ELN, FGF18, GUCY1A1 +5 more | View in SCUBA |
| Fibroblasts | PI16+ Fibroblast Identity ECM production | AADACL2, ADAMTSL4, ARHGAP29, C16orf89, CADM3, CD248, CLEC3B, CYP4B1 +10 more | View in SCUBA |
| Glial cells | Glial ECM Scaffold ECM remodeling | CADM1, COL9A3, FGL2, ISLR, ITIH5, LTBP4, MAMDC2, PCSK2 +1 more | View in SCUBA |
| Pericytes | Arterial Pericyte Identity Developmental | ATP13A3, BMX, GJA5, KCTD12, LTC4S, PLLP, SEMA3G, TMEM100 +1 more | View in SCUBA |
About the gene
| Chromosome | 3: 13549125-13638422 |
|---|---|
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins |
Function
Its binding to fibronectin and some other ligands is calcium dependent. May act as an adapter that mediates the interaction between FBN1 and ELN
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.