AKAP6 — A-kinase anchoring protein 6
AKAP6 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
AKAP6's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Glial cells | Glial Neural Scaffolding Cytoskeletal | ARHGAP24, COL5A3, EIF4G2, NFIX, PPP1R12B, SCAF11, SEMA6D, USP53 | View in SCUBA |
| Smooth muscle cells | Cytoskeletal Scaffolding Cytoskeletal | C3orf70, CNST, CTTNBP2, DACT3, IQGAP1, KIF13A, KLHL23, NTF3 +8 more | View in SCUBA |
About the gene
| Synonyms | ADAP6, AKAP100, KIAA0311, mAKAP, PRKA6 |
|---|---|
| Chromosome | 14: 32329298-32837684 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
Function
Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the nuclear membrane or sarcoplasmic reticulum. May act as an adapter for assembling multiprotein complexes
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.