SCUBA

LIMD2 — LIM domain containing 2

LIMD2 belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

LIMD2's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsB-cell activation signaling
B cell maturation
CD180, CYB561A3, DAAM1, ETS1, STX7, TERF2IP, UCP2, ZNF106View in SCUBA
CD4⁺ T cellsLeukocyte adhesion signaling
migration & adhesion
ARHGDIB, BIN1, CD37, DGKA, DGKZ, EIF3F, EIF3L, EIF4B +22 moreView in SCUBA
EndothelialVenous EC Identity
Endothelial cell development
ALDH1A1, ALDH3A2, ASGR1, ATP9A, BMP2K, DSP, FAM107B, KIAA1522 +12 moreView in SCUBA
Gamma-delta T cellsEffector IFN Response
cytotoxicity
AGTRAP, ANXA1, B2M, CYBA, EMP3, FXYD5, GZMM, IFITM1 +9 more
Innate lymphoid cellsILC1 Lymphocyte Signaling
Immune regulation
CDIPT, CNPY3, DBNL, ENG, IL16, LSM2, MAPKAPK3, PHYKPL +11 moreView in SCUBA
Mucosal-associated invariant T cellCytotoxic Effector
cytotoxicity
ANXA4, CCM2, CD320, CST7, DYNLRB1, GZMM, MCUB, MGMT +10 more
Natural Killer cellsInnate Sensing NK Regulation
Immune regulation
ADRB2, DTHD1, FCRL6, LFNG, PLEK, PRR5L, PYHIN1, UBE2F +1 moreView in SCUBA
NeutrophilsNeutrophil Motility Cytoskeleton
Migration & adhesion
CDKN2D, CNN2, COTL1, CST7, GLIPR1, GMFG, GNB2, GPSM3 +9 more

About the gene

SynonymsMGC10986
Chromosome17: 63695888-63701172
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins

Function

Acts as an activator of the protein-kinase ILK, thereby regulating cell motility

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.