SCUBA

CD2BP2 — CD2 cytoplasmic tail binding protein 2

CD2BP2 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

CD2BP2's module in each cell type

Cell typeModuleShares the module with
CD4⁺ T cellsProteasome translation
Housekeeping
ADRM1, CDV3, CST7, EHBP1L1, EIF3J, ENO1, HSBP1, MAPKAPK2 +5 moreView in SCUBA
CD8⁺ T cellsCytotoxic Exhausted CD8
Exhaustion
CCL3, CLEC2D, CTSD, DUSP4, GZMB, NDFIP2, PHLDA1, PRF1 +2 moreView in SCUBA
Innate lymphoid cellsmRNA Translation
RNA processing & translation
ABHD14B, ARHGDIA, EEF2, EIF3L, GYPC, H2AJ, HNRNPA0, HNRNPDL +6 moreView in SCUBA

About the gene

SynonymsLIN1, PPP1R59, Snu40, U5-52K
Chromosome16: 30350773-30355308
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins
Biological processmRNA processing, mRNA splicing

Function

Involved in pre-mRNA splicing as component of the U5 snRNP complex that is involved in spliceosome assembly

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.