CDKN2D — Cyclin dependent kinase inhibitor 2D
CDKN2D belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CDKN2D's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | mRNA Splicing Factors RNA processing | ARGLU1, CLK1, ERO1B, FUS, GLS, HNRNPA2B1, ID1, MAT2A +8 more | View in SCUBA |
| Innate lymphoid cells | NK Homing Circulating Homing & TEM | ADD3, ANXA1, APOBEC3G, C16orf54, C1orf162, CAPG, CASP4, CAST +37 more | View in SCUBA |
| Monocytes | Monocyte Innate Surveillance Innate immunity | FCN1, ICAM3, MMP25, PADI2, RPH3A, S100P, TESC, TUBA4A | View in SCUBA |
| Mucosal-associated invariant T cell | Cytotoxic Lymphocyte Program cytotoxicity | ANXA11, CYB5A, EMP3, ETHE1, FLT3LG, GLIPR2, LDHB, LTB +9 more | |
| Neutrophils | Neutrophil Motility Cytoskeleton Migration & adhesion | CNN2, COTL1, CST7, GLIPR1, GMFG, GNB2, GPSM3, JPT1 +9 more |
About the gene
| Synonyms | INK4D, p19 |
|---|---|
| Chromosome | 19: 10566460-10569059 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Cell cycle |
Function
Interacts strongly with CDK4 and CDK6 and inhibits them
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.