SCUBA

P4HA2 — Prolyl 4-hydroxylase subunit alpha 2

P4HA2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

P4HA2's module in each cell type

Cell typeModuleShares the module with
Smooth muscle cellsMatrix-integrin interaction
ECM remodeling
C1S, EML1, FBN1, ITGA1, ITGAV, LRP1, VMP1View in SCUBA

About the gene

SynonymsC-P4Halpha(II), lncRNA-PE
Chromosome5: 132190147-132295315
Predicted locationIntracellular
Essential geneNo
Protein classDisease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins
Molecular functionDioxygenase, Oxidoreductase

Function

Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.