ENOSF1 — Enolase superfamily member 1
ENOSF1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ENOSF1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Pre-mRNA Splicing RNA processing & translation | AKAP7, ARID1A, CEP57, EIF4E, GGNBP2, HERC5, HNRNPD, KTN1 +8 more | |
| Lymphatic endothelial | Hypoxia Response Stress | CNTNAP3B, FBN1, FKBP5, FOXP2, HIF3A, HMCN1, KAT2B, MAP3K1 +11 more | View in SCUBA |
| Macrophages | Monocyte Lipid Metabolism Lipid metabolism | ATP13A3, CEP170, CHIC2, COQ10B, CSGALNACT2, HIPK2, HMGXB3, KIF13A +14 more | View in SCUBA |
About the gene
| Synonyms | FUCD, HSRTSBETA, rTS, TYMSAS |
|---|---|
| Chromosome | 18: 670318-712662 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Predicted intracellular proteins |
| Molecular function | Isomerase, Lyase |
Function
Plays a role in the catabolism of L-fucose, a sugar that is part of the carbohydrates that are attached to cellular glycoproteins. Catalyzes the dehydration of L-fuconate to 2-keto-3-deoxy-L-fuconate by the abstraction of the 2-proton to generate an enediolate intermediate that is stabilized by the magnesium ion
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.