SCUBA

KTN1 — Kinectin 1

KTN1 belongs to a gene co-expression module in 10 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

KTN1's module in each cell type

Cell typeModuleShares the module with
EndothelialER-Golgi Trafficking
Protein processing & ER
ATL3, DIAPH2, ECE1, EID1, GOLIM4, MAGT1, PGK1, SHISA5 +4 moreView in SCUBA
EnterocytesEpithelial junction adhesion
Migration & adhesion
ADGRG6, CEACAM6, CTNNB1, DSG2, NCOA7, SAMD9L, SH3GLB1, TOP1 +2 moreView in SCUBA
FibroblastsER Protein Folding
Housekeeping
AHCYL1, CANX, CSNK1A1, HNRNPK, HSP90B1, JAK1, KDELR1, LAMTOR1 +10 moreView in SCUBA
Gamma-delta T cellsPre-mRNA Splicing
RNA processing & translation
AKAP7, ARID1A, CEP57, EIF4E, ENOSF1, GGNBP2, HERC5, HNRNPD +8 more
Glial cellsActin Remodeling Migration
migration & adhesion
CALD1, CAST, CD46, GLIPR2, GSTK1, SPATA13, TCEAL4View in SCUBA
Innate lymphoid cellsPre-mRNA Splicing
RNA processing & translation
AAK1, CDC42SE2, CIB1, DDX46, HNRNPM, KRT10, LARP7, LYRM2 +3 moreView in SCUBA
Lymphatic endothelialAntigen Presentation IFN
Inflammation
ADAR, GPRC5B, HLA-F, PARP14, PTTG1IP, SCARB2, TAPBP, TMEM123 +2 moreView in SCUBA
MacrophagesmRNA Splicing Processing
Housekeeping
AP3D1, BAZ1B, CCDC47, CHTOP, CTCF, EIF1AX, EIF3A, HDLBP +29 moreView in SCUBA
PericytesER-Actin Cytoskeletal
Cytoskeletal
A2M, CSDE1, GTF2I, IQGAP1, MAP4K4, SEC62, SERINC1, WASF2View in SCUBA
Smooth muscle cellsActin remodeling
Cytoskeletal
ARPC5, CALM1, GADD45GIP1, GNAS, HNRNPM, PLS3, SERBP1View in SCUBA

About the gene

SynonymsCG1, KIAA0004, KNT
Chromosome14: 55559072-55701526
Predicted locationIntracellular, Membrane
Essential geneNo
Protein classCancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins

Function

Receptor for kinesin thus involved in kinesin-driven vesicle motility. Accumulates in integrin-based adhesion complexes (IAC) upon integrin aggregation by fibronectin

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.