FCRL6 — Fc receptor like 6
FCRL6 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
FCRL6's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | NK-like Terminal Differentiation T cell maturation | EPB41L4A, JAZF1, LILRB1, MLC1, PRR5L, SYT11, ZEB2 | |
| Natural Killer cells | Innate Sensing NK Regulation Immune regulation | ADRB2, DTHD1, LFNG, LIMD2, PLEK, PRR5L, PYHIN1, UBE2F +1 more | View in SCUBA |
About the gene
| Synonyms | FcRH6, FLJ16056, IFGP6 |
|---|---|
| Chromosome | 1: 159800511-159816257 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | Receptor |
Function
Acts as a MHC class II receptor. When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8(+) T cells. Does not act as an Fc receptor.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.