GFPT2 — Glutamine-fructose-6-phosphate transaminase 2
GFPT2 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GFPT2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Th17/MAIT type-17 Th17 fate | AKT1S1, CA10, CA2, CCL20, CEBPD, IL22, IL4I1, LRRN3 +9 more | View in SCUBA |
| Fibroblasts | Cytokine Inflammatory Response Inflammatory | CXCL2, DNAJB4, HES4, MAP3K8, MMP19, RASL11A, RGCC, RND3 +4 more | View in SCUBA |
| Mucosal-associated invariant T cell | Tc17 / MAIT17 Tc17 program | AHR, BAIAP2, CA10, CCR9, HIC1, IL17A, IL2, ITGA1 +5 more |
About the gene
| Synonyms | GFAT2 |
|---|---|
| Chromosome | 5: 180300698-180353336 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | Aminotransferase, Transferase |
Function
Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.