RND3 — Rho family GTPase 3
RND3 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RND3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Cytokine Inflammatory Response Inflammatory | CXCL2, DNAJB4, GFPT2, HES4, MAP3K8, MMP19, RASL11A, RGCC +4 more | View in SCUBA |
| Glial cells | RNA Splicing Processing RNA processing & translation | DDX3X, DDX5, HNRNPA2B1, HNRNPAB, HNRNPDL, HNRNPH1, MAFB, NES +2 more | View in SCUBA |
| Smooth muscle cells | BMP/TGF-beta response Activation | APBB2, GLS, ID1, ID2, IRS2, KLF10, SEC11C, SIPA1L2 +1 more | View in SCUBA |
About the gene
| Synonyms | ARHE, Rho8, RhoE |
|---|---|
| Chromosome | 2: 150468195-150539011 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.